Product Name: GW 788388
Synonyms: 4-[4-[3-(2-pyridinyl)-1H-pyrazol-4-yl]-2-pyridinyl]-N-(tetrahydro-2H-pyran-4-yl)-benzamideMedchemexpress
Product Overview: A selective inhibitor of TGF-β type 1 receptor (TGFBR1 or ALK5; IC50 = 18 nM); inhibits the expression of collagen type I in cells (IC50 = 93 nM) and in mice when given orally at 10 mg/kg once a day; reduces typical features of fibrosisGW 788388 is a
Shipping: wet ice
CAS NO: 121917-57-5 Product: (-)-MK 801 (Maleate)
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C25H23N5O2
SMILES: O=C(C1=CC=C(C2=NC=CC(C3=CNN=C3C4=CC=CC=N4)=C2)C=C1)NC5CCOCC5Others inhibitors
Molecular Weight: 425.5
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://aac.asm.org/content/57/9/4410.abstract
