Product Name: CGP 57380
Synonyms: N3-(4-fluorophenyl)-1H-pyrazolo[3,4-d]pyrimidine-3,4-diamine MNK1 InhibitorWeb Site click
Product Overview: A selective inhibitor of MNK1 in vitro (IC50 = 2.2 μM), with no inhibitory activity against p38, JNK1, ERK1/2, PKC, or Src-like kinases; blocks the phosphorylation of eIF4E in response to TNF-α, arsenite, anisomycin, PMA, or fetal calf serum in 2
Shipping: wet ice
CAS NO: Product: Ciprofibrate D6
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C11H9FN6
SMILES: Fc1ccc(cc1)Nc1n[nH]c2ncnc(N)c12GHSR inhibitors
Molecular Weight: 244.2
Formulation: A crystalline solid
Purity: ≥95%PubMed ID:http://aac.asm.org/content/57/6/2596.abstract
