Product Name :
IWP L6
Description:
IWP-L6, also known as PORCN Inhibitor III and Wnt Pathway Inhibitor XIX, is a potent inhibitor of PORCN (EC50 = 0.5 nM). Porcupine is a member of the membrane-bound O-acyltransferase family of proteins. It catalyzes the palmitoylation of Wnt proteins, a process required for their secretion and activity.
CAS:
1427782-89-5
Molecular Weight:
472.58
Formula:
C25H20N4O2S2
Chemical Name:
2-(4-oxo-3-phenyl-3H,4H,6H,7H-thieno[3,2-d]pyrimidin-2-ylsulfanyl)-N-(5-phenylpyridin-2-yl)acetamide
Smiles :
O=C(CSC1=NC2CCSC=2C(=O)N1C1C=CC=CC=1)NC1=CC=C(C=N1)C1C=CC=CC=1
InChiKey:
QESQGTFWEQMCMH-UHFFFAOYSA-N
InChi :
InChI=1S/C25H20N4O2S2/c30-22(28-21-12-11-18(15-26-21)17-7-3-1-4-8-17)16-33-25-27-20-13-14-32-23(20)24(31)29(25)19-9-5-2-6-10-19/h1-12,15H,13-14,16H2,(H,26,28,30)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.Berotralstat manufacturer
Shelf Life:
≥360 days if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.Tebotelimab supplier
Additional information:
IWP-L6, also known as PORCN Inhibitor III and Wnt Pathway Inhibitor XIX, is a potent inhibitor of PORCN (EC50 = 0.PMID:32827401 5 nM). Porcupine is a member of the membrane-bound O-acyltransferase family of proteins. It catalyzes the palmitoylation of Wnt proteins, a process required for their secretion and activity.|Product information|CAS Number: 1427782-89-5|Molecular Weight: 472.58|Formula: C25H20N4O2S2|Chemical Name: 2-(4-oxo-3-phenyl-3H,4H,6H,7H-thieno[3,2-d]pyrimidin-2-ylsulfanyl)-N-(5-phenylpyridin-2-yl)acetamide|Smiles: O=C(CSC1=NC2CCSC=2C(=O)N1C1C=CC=CC=1)NC1=CC=C(C=N1)C1C=CC=CC=1|InChiKey: QESQGTFWEQMCMH-UHFFFAOYSA-N|InChi: InChI=1S/C25H20N4O2S2/c30-22(28-21-12-11-18(15-26-21)17-7-3-1-4-8-17)16-33-25-27-20-13-14-32-23(20)24(31)29(25)19-9-5-2-6-10-19/h1-12,15H,13-14,16H2,(H,26,28,30)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥360 days if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|
