XIAP Antibody

Additional Information:
|Introduction BIRC4, baculoviral repeat-containing protein 4 is also known as X (X-linked inhibitor of apoptosis protein). The BIRC4 gene comprises 6 exons. This gene is mapped to chromosome Xq25. This gene encodes a protein that belongs to a family of apoptotic suppressor proteins. Members of this family share a conserved motif termed, baculovirus repeat, which is necessary for their anti-apoptotic function. This protein functions through binding to tumor necrosis factor receptor-assoc factors TRAF1 and TRAF2 and inhibits apoptosis induced by menadione, a potent inducer of free radicals, and interleukin 1-beta converting enzyme. This protein also inhibits at least two members of the cas|WB: 0.1-0.5 ug/ml IHC-P: 0.5-1 ug/ml. Reactivity: Human, Rat, Mouse. Immunogen: A synthetic peptide corresponding to a sequence at the N-terminal of human X different from the related mouse sequence by two amino acids. Purification: Immunogen affinity purified. Form of Antibody: Lyophilized. Isotype: Rabbit IgG. Storage/Stability: Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original v after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing. |Other X Antibody: X (Ab-87) Polyclonal Antibody