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Product Name :
Vinculin Antibody

EN
Metavinculin; VCL; VINC

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Background:
Vinculin is a cytoskeletal protein associated with the cytoplasmic face of both cell-cell and cell-extracellular matrix adherens-type junctions, where it is thought to function as one of several interacting proteins involved in anchoring F-actin to the membrane . both human and chicken embryo sequences of vinculin contain 1,066 amino acids and, furthermore, that the 2 proteins exhibit a high level of sequence identity (greater than 95%). Vinculinis mapped to 10q22.1-q23. PA000102-MA1103: Vinc?lin Monoclonal Antibody Mouse Monoclonal Antibody. Specificity/Sensitivity: Human, mouse, rat, rabbit, chicken. No cross reactivity with other proteins. Applications: Western blot: At 1-2ug/ml with the appropriate system to detect vinculin in cells and tissues. Immunohistochemistry(F): At 2-4ug/ml to detect vinculin in formalin or acetone fixed tissues. Reactivity: Human, Mouse, Rat, Rabbit, Chicken. Immunogen: Human vinculin, purified from uterus. Purification: Purified by the goat anti-mouse IgG affinity chromatography. Form of Antibody: Lyophilized from 1.2% sodium acetate, with 2mg BSA and 0.01mg NaN3 as preservative. Isotype: Mouse IgG1. Storage/Stability: Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original vial after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing.

Additional Information:
|Background Vinculin is a cytoskeletal protein assoc with the cytoplasmic face of both cell-cell and cell-extracellular matrix adherens-type junctions, where it is thought to function as one of several interacting proteins involved in anchoring F-actin to the membrane . both human and chicken embryo sequences of vinculin contain 1,066 amino acids and, furthermore, that the 2 proteins exhibit a high level of sequence identity (greater than 95%). Vinculinis mapped to 10q22.1-q23. | Vinc?lin Monoclonal Antibody Mouse Monoclonal Antibody. Specificity/Sensitivity: Human, mouse, rat, rabbit, chicken. No cross reactivity with other proteins. Applications: Western blot: At 1-2ug/ml with the appropr system to detect vinculin in cells and tissues. Immunohistochemistry(F): At 2-4ug/ml to detect vinculin in formalin or acetone fixed tissues. Reactivity: Human, Mouse, Rat, Rabbit, Chicken. Immunogen: Human vinculin, purified from uterus. Purification: Purified by the goat anti-mouse IgG affinity chromatography. Form of Antibody: Lyophilized from 1.2% sodium acetate, with 2mg BSA and 0.01mg NaN3 as preservative. Isotype: Mouse IgG1. Storage/Stability: Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original v after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing.

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: signsin1dayinc