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Product Name :
TNF alpha Antibody

EN
Tumor necrosis factor α Antibody

Additional Information:
|Background Tumor necrosis factor-alpha (TNFA) also kowns as TNFR1, It is a potent cytokine, elicits a broad spectrum of biologic responses which are med by binding to a cell surface receptor. There are 2 different proteins that serve as major receptors for TNF-alpha, one assoc with myeloid cells and one assoc with epithel cells. TNFR1 maps to 12p13. TNFR1 signaling is also known to activate the transcription factor NF-kap|Tumour necrosis factor α (TNFα). Applications: Indirect ELISA: 1 ug/ml as primary antibody. Reactivity: Human. Immunogen: Recombinant human TNFα. Purification: purified from mouse ascites through a Protein A column. Form of Antibody: 1 ug/ml in PBS containing 0.1% sodium azide as a preservative. Clone No: KT31. Isotype: Mouse IgG2a. Storage/Stability: Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original v after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing.

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: signsin1dayinc