Caveolin 1 Antibody

Additional Information:
|Introduction The scaffolding protein encoded by the CAV1 gene is the key component of the caveolae plasma membranes found in most cell types. Cholesterol is vital for caveolae formation and maintenance, and caveolae structure is highly sensitive to cholesterol depletion or treatment with cholesterol binding drugs. CAV1 can tightly and specifically bind free cholesterol and artific cholesterol containing vesicles. Caveolin 1 links integrin subunits to the tyrosine kinase FYN, which is an init step in coupling integrins to the Ras-ERK |WB, ELISA. Reactivity: Human. Immunogen: Anti-human CAV1 mAb, is derived from hybridization of mouse FO myeloma cells with spleen cells from BALB/c mice immunized with recombinant human CAV1 amino acids 1-104 purified from E. coli. Purification: CAV1 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography. Form of Antibody: 1 ug/ml containing PBS, pH-7.4, & 0.1% Sodium Azide. Storage/Stability: Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original v after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing.