STAT3 Antibody

Background:
The transcription factor, signal transducer and activator of transcription-3 (STAT-3) is the most pleiotropic member of the signal transducer and activator of transcription (STAT) family of transcription factors and mediates pivotal responses for the cytokine family. The mouse STAT3 gene contains 24 exons and spans 30 kb. The translation initiation codon is in exon 2, and the stop codon is in exon 24. STAT3 is mapped to 17q21, it contributes to various physiological processes. Hepatic STAT-3 signaling is thus essential for normal glucose homeostasis and may provide new therapeutic targets for diabetes mellitus. PA000234-PA1108: STAT3 Polyclonal Antibody Rabbit Polyclonal Antibody. Specificity/Sensitivity: Human, mouse, rat. No cross reactivity with other proteins. Applications: WB 0.1-0.5 ug/ml IHC-P 0.5-1 ug/ml ICC 1 ug/ml. Reactivity: Human, Mouse, Rat. Immunogen: A synthetic peptide corresponding to a sequence at the C-terminal of human STAT3, identical to the related rat and mouse sequence. Purification: Immunogen affinity purified. Form of Antibody: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3. Isotype: Rabbit IgG. Storage/Stability: Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original vial after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing. Other STAT3 Antibodies: Stat3 Polyclonal Antibody STAT3 Polyclonal Antibody STAT3 Polyclonal Antibody STAT3 (Ab-727) Polyclonal Antibody STAT3 (Ab-705) Polyclonal Antibody STAT3 Protein: Recombinant Human STAT3 Protein