Product Name :
SMAD4 Antibody
EN
DPC4 Antibody
Source:
Molecular Weight:
Activity :
Purity:
Endotoxin :
Formulation:
Reconstitution :
Shipping:
Stability & Storage:
Form of Antibody :
Clone:
Isotype:
Background:
SMAD4 plays a pivotal role in signal transduction of the transforming growth factor beta superfamily cytokines by mediating transcriptional activation of target genes. Smad4 signalling in T cells is required for suppression of gastrointestinal cancer. Mutational inactivation of SMAD4 causes TGF-beta unresponsiveness and gave a basis for understanding the physiologic role of this gene in tumorigenesis. Mutations in DPC4 (SMAD4) cause juvenile polyposis syndrome, but only account for a minority of cases. PA000086-MA1089: Smad4 DPC4 Monoclonal Antibody Mouse Monoclonal Antibody. Specificity/Sensitivity: Human. No cross reactivity with other proteins. Applications: Western blot: At 2-4 ug/ml with the appropriate system to detect Smad4 in cells and tissues. Reactivity: Human. Immunogen: Recombinant human Smad4 (DPC4). Purification: Purified by the goat anti-mouse IgG affinity chromatography. Form of Antibody: Lyophilized from 1.2% sodium acetate, with 2 mg BSA and 0.01 mg NaN3 as preservative. Clone: IMD-89. Isotype: Mouse IgG1. Storage/Stability: Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original vial after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing. Other SMAD4 Antibodies: Smad4 Polyclonal Antibody Smad4 Polyclonal Antibody Smad4 Polyclonal Antibody SMAD4 Proteins: Recombinant Human SMAD4 protein Recombinant Human SMAD4 protein
Additional Information:
|Background SMAD4 plays a pivotal role in signal transduction of the transforming growth factor beta superfamily cytokines by med transcriptional activation of target genes. Smad4 signalling in T cells is required for suppression of gastrointestinal cancer. Mutational inactivation of SMAD4 causes TGF-beta unresponsiveness and gave a basis for understanding the physiologic role of this gene in tumorigenesis. Mutations in DPC4 (SMAD4) cause juvenile polyposis syndrome, but only account for a minority of cases. | Smad4 DPC4 Monoclonal Antibody Mouse Monoclonal Antibody. Specificity/Sensitivity: Human. No cross reactivity with other proteins. Applications: Western blot: At 2-4 ug/ml with the appropr system to detect Smad4 in cells and tissues. Reactivity: Human. Immunogen: Recombinant human Smad4 (DPC4). Purification: Purified by the goat anti-mouse IgG affinity chromatography. Form of Antibody: Lyophilized from 1.2% sodium acetate, with 2 mg BSA and 0.01 mg NaN3 as preservative. Clone: IMD-89. Isotype: Mouse IgG1. Storage/Stability: Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original v after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing. |Other SMAD4 Antibodies: Smad4 Polyclonal Antibody Smad4 Polyclonal Antibody Smad4 Polyclonal Antibody |SMAD4 Proteins: Recombinant Human SMAD4 protein Recombinant Human SMAD4 protein
Related websites: https://www.medchemexpress.com/antibodies.html
Popular product recommendations:
RNA Polymerase II Subunit B1 Antibody
N Cadherin Antibody
CBR1 Antibody (YA810): CBR1 Antibody (YA810) is a non-conjugated and Mouse origined monoclonal antibody about 30 kDa, targeting to CBR1 (2C9). It can be used for WB,ICC/IF assays with tag free, in the background of Human.
