SARS-Spike Antibody

Additional Information:
|Introduction SARS Coronavirus is an enveloped virus containing three outer structural proteins, namely the membrane (M), envelope (E), and spike (S) proteins. Spike (S)-glycoprotein of the virus interacts with a cellular receptor and med membrane fusion to allow viral entry into susceptible target cells. Accordingly, S-protein plays an important role in virus infection cycle and is the primary target of neutralizing antibodies. | SARS-Spike Polyclonal Antibody Rabbit Polyclonal Antibody. Applications: This polyclonal antibody can be used for detection of SARS Spike protein in Western blot. Full-length Spike protein transfected into UM92 cells was used as a positive control and an approximate 139KDa band is detected. Western blot analysis of Spike in (A) transfected and (B) untransfected mouse melanoma cell lysate at a concentration of 0.05 ug/ml. Immunogen: The antibody was developed by immunizing rabbits with synthetic peptides corresponding to amino acids 1124-1140 of the putative SARS Spike glycoprotein (Genbank accession no. NP_828851). Form of Antibody: 100ugs in 200ul PBS containing 0.2% gelatin and 0.05% sodium azide. Isotype: Rabbit IgG. Storage/Stability: Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original v after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing.