Product Name :
Methyldopa hydrate
Description:
Methyldopa hydrate (L-(-)-α-Methyldopa hydrate), a potent antihyoertensive agent, is an alpha-adrenergic agonist (selective for α2-adrenergic receptors). Methyldopa hydrate is a prodrug and is metabolized (α-Methylepinephrine) in the central nervous system.
CAS:
41372-08-1
Molecular Weight:
238.24
Formula:
C20H32N2O11
Chemical Name:
(S)-2-amino-3-(3, 4-dihydroxyphenyl)-2-methylpropanoic acid sesquihydrate
Smiles :
O.O.O.C[C@](N)(CC1=CC(O)=C(O)C=C1)C(O)=O.C[C@](N)(CC1=CC(O)=C(O)C=C1)C(O)=O
InChiKey:
YKFCISHFRZHKHY-NGQGLHOPSA-N
InChi :
InChI=1S/2C10H13NO4.3H2O/c2*1-10(11,9(14)15)5-6-2-3-7(12)8(13)4-6;;;/h2*2-4,12-13H,5,11H2,1H3,(H,14,15);3*1H2/t2*10-;;;/m00…/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Methyldopa hydrate (L-(-)-α-Methyldopa hydrate), a potent antihyoertensive agent, is an alpha-adrenergic agonist (selective for α2-adrenergic receptors). Methyldopa hydrate is a prodrug and is metabolized (α-Methylepinephrine) in the central nervous system.|Product information|CAS Number: 41372-08-1|Molecular Weight: 238.24|Formula: C20H32N2O11|Chemical Name: (S)-2-amino-3-(3, 4-dihydroxyphenyl)-2-methylpropanoic acid sesquihydrate|Smiles: O.O.O.C[C@](N)(CC1=CC(O)=C(O)C=C1)C(O)=O.C[C@](N)(CC1=CC(O)=C(O)C=C1)C(O)=O|InChiKey: YKFCISHFRZHKHY-NGQGLHOPSA-N|InChi: InChI=1S/2C10H13NO4.3H2O/c2*1-10(11,9(14)15)5-6-2-3-7(12)8(13)4-6;;;/h2*2-4,12-13H,5,11H2,1H3,(H,14,15);3*1H2/t2*10-;;;/m00…/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 33.Vadadustat Cancer 33 mg/mL (139.Eblasakimab Purity & Documentation 90 mM; Need ultrasonic).PMID:32924642 H2O : 1 mg/mL (4.20 mM; Need ultrasonic).|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vivo:|Methyldopa hydrate (L-(-)-α-Methyldopa hydrate; 200 mg/kg; i.p.) decreases the hyperglycemic response in the first 2 hr after Dieldrin treatment.|Products are for research use only. Not for human use.|
