Product Name :
3′-Hydroxypterostilbene
Description:
3′-Hydroxypterostilbene, a natural pterostilbene analogue, effectively inhibits the growth of human colon cancer cells (IC50s of 9.0, 40.2, and 70.9 µM for COLO 205, HCT-116, and HT-29 cells, respectively) by inducing apoptosis and autophagy. 3′-Hydroxypterostilbene inhibits the PI3K/Akt/mTOR/p70S6K, and p38MAPK pathways and activates the ERK1/2, JNK1/2 MAPK pathways.
CAS:
475231-21-1
Molecular Weight:
272.30
Formula:
C16H16O4
Chemical Name:
4-[(E)-2-(3, 5-dimethoxyphenyl)ethenyl]benzene-1, 2-diol
Smiles :
COC1C=C(C=C(C=1)OC)/C=C/C1=CC(O)=C(O)C=C1
InChiKey:
UQRBFXIUUDJHSN-ONEGZZNKSA-N
InChi :
InChI=1S/C16H16O4/c1-19-13-7-12(8-14(10-13)20-2)4-3-11-5-6-15(17)16(18)9-11/h3-10,17-18H,1-2H3/b4-3+
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Andecaliximab} site|{Andecaliximab} Metabolic Enzyme/Protease|{Andecaliximab} Biological Activity|{Andecaliximab} In Vitro|{Andecaliximab} manufacturer|{Andecaliximab} Autophagy}
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.{{Levofloxacin} MedChemExpress|{Levofloxacin} Antibiotic|{Levofloxacin} Purity & Documentation|{Levofloxacin} References|{Levofloxacin} custom synthesis|{Levofloxacin} Epigenetics}
Additional information:
3′-Hydroxypterostilbene, a natural pterostilbene analogue, effectively inhibits the growth of human colon cancer cells (IC50s of 9.PMID:33183172 0, 40.2, and 70.9 µM for COLO 205, HCT-116, and HT-29 cells, respectively) by inducing apoptosis and autophagy. 3′-Hydroxypterostilbene inhibits the PI3K/Akt/mTOR/p70S6K, and p38MAPK pathways and activates the ERK1/2, JNK1/2 MAPK pathways.|Product information|CAS Number: 475231-21-1|Molecular Weight: 272.30|Formula: C16H16O4|Chemical Name: 4-[(E)-2-(3, 5-dimethoxyphenyl)ethenyl]benzene-1, 2-diol|Smiles: COC1C=C(C=C(C=1)OC)/C=C/C1=CC(O)=C(O)C=C1|InChiKey: UQRBFXIUUDJHSN-ONEGZZNKSA-N|InChi: InChI=1S/C16H16O4/c1-19-13-7-12(8-14(10-13)20-2)4-3-11-5-6-15(17)16(18)9-11/h3-10,17-18H,1-2H3/b4-3+|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 125 mg/mL (459.05 mM; Need ultrasonic)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|References:|Cheng TC, et al. Potent anti-cancer effect of 3′-hydroxypterostilbene in human colon xenograft tumors. PLoS One. 2014 Nov 12;9(11):e111814.Products are for research use only. Not for human use.|
