Product Name :
VI 16832
Description:
VI 16832 is a broad spectrum Type I kinase inhibitor which can be used as an enrichment tool for the comparative expression analysis of protein kinases in different cancer cell lines.
CAS:
1430218-51-1
Molecular Weight:
391.47
Formula:
C22H25N5O2
Chemical Name:
2-{[4-(2-aminoethoxy)phenyl]amino}-8-{bicyclo[2.2.1]heptan-2-yl}-7H,8H-pyrido[2,3-d]pyrimidin-7-one
Smiles :
NCCOC1C=CC(=CC=1)NC1=NC2=C(C=N1)C=CC(=O)N2C1CC2CC1CC2
InChiKey:
RCSLGYIVHUXZCI-UHFFFAOYSA-N
InChi :
InChI=1S/C22H25N5O2/c23-9-10-29-18-6-4-17(5-7-18)25-22-24-13-16-3-8-20(28)27(21(16)26-22)19-12-14-1-2-15(19)11-14/h3-8,13-15,19H,1-2,9-12,23H2,(H,24,25,26)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
VI 16832 is a broad spectrum Type I kinase inhibitor which can be used as an enrichment tool for the comparative expression analysis of protein kinases in different cancer cell lines.|Product information|CAS Number: 1430218-51-1|Molecular Weight: 391.47|Formula: C22H25N5O2|Chemical Name: 2-{[4-(2-aminoethoxy)phenyl]amino}-8-{bicyclo[2.2.1]heptan-2-yl}-7H,8H-pyrido[2,3-d]pyrimidin-7-one|Smiles: NCCOC1C=CC(=CC=1)NC1=NC2=C(C=N1)C=CC(=O)N2C1CC2CC1CC2|InChiKey: RCSLGYIVHUXZCI-UHFFFAOYSA-N|InChi: InChI=1S/C22H25N5O2/c23-9-10-29-18-6-4-17(5-7-18)25-22-24-13-16-3-8-20(28)27(21(16)26-22)19-12-14-1-2-15(19)11-14/h3-8,13-15,19H,1-2,9-12,23H2,(H,24,25,26)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 33.{{Isosorbide mononitrate} web|{Isosorbide mononitrate} Autophagy|{Isosorbide mononitrate} Technical Information|{Isosorbide mononitrate} In Vitro|{Isosorbide mononitrate} supplier|{Isosorbide mononitrate} Autophagy} 33 mg/mL (85.14 mM; Need ultrasonic).|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.{{Dopamine-d5} medchemexpress|{Dopamine-d5} GPCR/G Protein|{Dopamine-d5} Technical Information|{Dopamine-d5} Formula|{Dopamine-d5} manufacturer|{Dopamine-d5} Cancer} |Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|VI 16832 is a broad spectrum Type I kinase inhibitor.PMID:32536211 Phosphoproteomics analysis of VI 16832-enriched fractions from MV4-11, HCT116, or 435S cells results in more than 8500 phosphopeptide identifications. These translate into almost 1700 distinct phosphopeptide species derived from 212 different members of the protein kinase superfamily. Analysis of VI 16832-retained proteins from the three cancer cell lines considerably increases the overall number of identified phosphorylation sites on protein kinases. Considering the sum of all phosphopeptide intensities as a measure for VI 16832-enriched protein amount, more than 80% is derived from protein kinases.|Products are for research use only. Not for human use.|
