Product Name :
KB02-COOH
Description:
KB02-COOH is a fragment of synthesis of ubiquitin E3 ligase ligand KB02. KB02 can be used in the synthesis of PROTAC, such as KB02-JQ1 (HY-129917) and KB02-SLF (HY-129610).
CAS:
2375196-30-6
Molecular Weight:
283.71
Formula:
C13H14ClNO4
Chemical Name:
2-{[1-(2-chloroacetyl)-1, 2, 3, 4-tetrahydroquinolin-6-yl]oxy}acetic acid
Smiles :
OC(=O)COC1=CC2CCCN(C=2C=C1)C(=O)CCl
InChiKey:
ZWIYQLVGARZWJJ-UHFFFAOYSA-N
InChi :
InChI=1S/C13H14ClNO4/c14-7-12(16)15-5-1-2-9-6-10(3-4-11(9)15)19-8-13(17)18/h3-4,6H,1-2,5,7-8H2,(H,17,18)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{RGB-1} MedChemExpress|{RGB-1} NF-κB|{RGB-1} Purity & Documentation|{RGB-1} Description|{RGB-1} supplier}
Shelf Life:
≥360 days if stored properly.{{Dimethyl} medchemexpress|{Dimethyl} Immunology/Inflammation|{Dimethyl} Purity & Documentation|{Dimethyl} References|{Dimethyl} supplier|{Dimethyl} Epigenetic Reader Domain}
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
KB02-COOH is a fragment of synthesis of ubiquitin E3 ligase ligand KB02. KB02 can be used in the synthesis of PROTAC, such as KB02-JQ1 (HY-129917) and KB02-SLF (HY-129610).|Product information|CAS Number: 2375196-30-6|Molecular Weight: 283.PMID:32830380 71|Formula: C13H14ClNO4|Chemical Name: 2-{[1-(2-chloroacetyl)-1, 2, 3, 4-tetrahydroquinolin-6-yl]oxy}acetic acid|Smiles: OC(=O)COC1=CC2CCCN(C=2C=C1)C(=O)CCl|InChiKey: ZWIYQLVGARZWJJ-UHFFFAOYSA-N|InChi: InChI=1S/C13H14ClNO4/c14-7-12(16)15-5-1-2-9-6-10(3-4-11(9)15)19-8-13(17)18/h3-4,6H,1-2,5,7-8H2,(H,17,18)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 66.67 mg/mL (234.99 mM; Need ultrasonic)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥360 days if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|References:|Zhang X, et al. Electrophilic PROTACs that degrade nuclear proteins by engaging DCAF16. Nat Chem Biol. 2019 Jul;15(7):737-746.Products are for research use only. Not for human use.|
