Product Name :
Telbivudine
Description:
Telbivudine is an antiviral drug used in the treatment of hepatitis B infection. It is marketed by Swiss pharmaceutical company Novartis under the trade names Sebivo (Europe) and Tyzeka (United States). Clinical trials have shown it to be significantly more effective than lamivudine or adefovir, and less likely to cause resistance. Telbivudine is a synthetic thymidine nucleoside analogue; it is the L-isomer of thymidine.
CAS:
3424-98-4
Molecular Weight:
242.23
Formula:
C10H14N2O5
Chemical Name:
1-[(2S,4R,5S)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione
Smiles :
CC1=CN([C@@H]2C[C@@H](O)[C@H](CO)O2)C(=O)NC1=O
InChiKey:
IQFYYKKMVGJFEH-CSMHCCOUSA-N
InChi :
InChI=1S/C10H14N2O5/c1-5-3-12(10(16)11-9(5)15)8-2-6(14)7(4-13)17-8/h3,6-8,13-14H,2,4H2,1H3,(H,11,15,16)/t6-,7+,8+/m1/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Telbivudine is an antiviral drug used in the treatment of hepatitis B infection. It is marketed by Swiss pharmaceutical company Novartis under the trade names Sebivo (Europe) and Tyzeka (United States). Clinical trials have shown it to be significantly more effective than lamivudine or adefovir, and less likely to cause resistance. Telbivudine is a synthetic thymidine nucleoside analogue; it is the L-isomer of thymidine.|Product information|CAS Number: 3424-98-4|Molecular Weight: 242.23|Formula: C10H14N2O5|Synonym:|Epavudine|L-Thymidine|NV 02B|Sebivo|Chemical Name: 1-[(2S,4R,5S)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione|Smiles: CC1=CN([C@@H]2C[C@@H](O)[C@H](CO)O2)C(=O)NC1=O|InChiKey: IQFYYKKMVGJFEH-CSMHCCOUSA-N|InChi: InChI=1S/C10H14N2O5/c1-5-3-12(10(16)11-9(5)15)8-2-6(14)7(4-13)17-8/h3,6-8,13-14H,2,4H2,1H3,(H,11,15,16)/t6-,7+,8+/m1/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 50 mg/mL (206.{{Iniparib} MedChemExpress|{Iniparib} Cell Cycle/DNA Damage|{Iniparib} Protocol|{Iniparib} In Vitro|{Iniparib} supplier|{Iniparib} Autophagy} 42 mM; Need ultrasonic) H2O : 33.{{Pristinamycin} MedChemExpress|{Pristinamycin} Bacterial|{Pristinamycin} Protocol|{Pristinamycin} Description|{Pristinamycin} manufacturer|{Pristinamycin} Epigenetic Reader Domain} 33 mg/mL (137.PMID:24507727 60 mM; Need ultrasonic)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|References:|Kim JW, et al. Telbivudine: a novel nucleoside analog for chronic hepatitis B. Ann Pharmacother. 2006;40(3):472-478.Zobel T, et al. Telbivudine Reduces Parvovirus B19-Induced Apoptosis in Circulating Angiogenic Cells. Viruses. 2019;11(3):227. Published 2019 Mar 6.Products are for research use only. Not for human use.|
