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Product Name :
XAF1 Antibody

EN
XIAP Antibody, XIAP associated factor-1 Antibody

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Background:
XIAP associated factor-1, also known as XAF1, is a human gene. X-linked inhibitor of apoptosis (XIAP;MIM 300079) is a potent member of the IAP family. All members of this family possess baculoviral IAP (BIR) repeats, cysteine-rich domains of approximately 80 amino acids that bind and inhibit caspases.1 XAF1 antagonizes the anticaspase activity of XIAP and may be important in mediating apoptosis resistance in cancer cells.2 And alteration in XAF1 and XIAP RNA expression levels may lead to increased apoptotic resistance and proliferation due to unregulated XIAP function in cancer cells.1 PA000201-PA1218: XAF1 Polyclonal Antibody Rabbit Polyclonal Antibody. Specificity/Sensitivity: Human, mouse, rat. No cross reactivity with other proteins. Applications: WB 1 ug/ml IHC-P 0.5-1 ug/ml. Reactivity: Human. Immunogen: A synthetic peptide corresponding to a sequence at the C-terminal of human XAF1, identical to the related rat and mouse sequence. Purification: Immunogen affinity purified. Form of Antibody: Each vial contains 5mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3. Storage/Stability: Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original vial after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing.

Additional Information:
|Background X assoc factor-1, also known as XAF1, is a human gene. X-linked inhibitor of apoptosis (X 300079) is a potent member of the family. All members of this family possess baculoviral (BIR) repeats, cysteine-rich domains of approximately 80 amino acids that bind and inhibit cas|Human, mouse, rat. No cross reactivity with other proteins. Applications: WB 1 ug/ml IHC-P 0.5-1 ug/ml. Reactivity: Human. Immunogen: A synthetic peptide corresponding to a sequence at the C-terminal of human XAF1, identical to the related rat and mouse sequence. Purification: Immunogen affinity purified. Form of Antibody: Each v contains 5mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3. Storage/Stability: Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original v after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing.

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: signsin1dayinc