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Product Name :
VEGF Antibody

EN
Vascular Endothelial Growth Factor, vascular permeability factor, VPF, VEGF-A

Additional Information:
|Background VEGF, a homodimeric glycoprotein of relative molecular mass 45,000, is the only mitogen that specifically acts on endothel cells. It may be a major regulator of tumor angiogenesis in vivo.Vascular endothel growth factor is a mitogen primarily for vascular endothel cells. It is, however,structurally related to platelet-derived growth factor. VEGF shares homology with the PDGF A chain and B chain, including conservation of all 8 cysteines found in PDGFA and PDGFB. VEGF gene contains 8 exons. Vascular endothel growth factor (VEGF) induces remodeling and enhances TH2-med sensitization and inflammation in the lung. VEGF regulates haematopoietic stem cell survival by an internal autocrine loop mechanism. Vascular endothel growth factor (VEGF) stimulates neurogenesis in vitro and in vivo. | VEGF Monoclonal Antibody Mouse Monoclonal Antibody. Applications: Direct ELISA, Western Blot, Immuneprecipitation. By direct ELISA, 1:10,000 dilution will yield 0.15 O.D using alkaline phosphatase conjugated rabbit anti-mouse Ig (Jackson Laboratories). Reactivity: Human. Immunogen: r.HumanVEGF. Purification: Boric acid precipitation Protein concentration1 ug/ml in PBS (after reconstitution). Clone: NYRhVEGF. Isotype: NYRhVEGFM. Storage/Stability: Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original v after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing.

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: signsin1dayinc