VEGF Antibody

Background:
VEGF, a homodimeric glycoprotein of relative molecular mass 45,000, is the only mitogen that specifically acts on endothelial cells. It may be a major regulator of tumor angiogenesis in vivo.Vascular endothelial growth factor is a mitogen primarily for vascular endothelial cells. It is, however,structurally related to platelet-derived growth factor. VEGF shares homology with the PDGF A chain and B chain, including conservation of all 8 cysteines found in PDGFA and PDGFB. VEGF gene contains 8 exons. Vascular endothelial growth factor (VEGF) induces remodeling and enhances TH2-mediated sensitization and inflammation in the lung. VEGF regulates haematopoietic stem cell survival by an internal autocrine loop mechanism. Vascular endothelial growth factor (VEGF) stimulates neurogenesis in vitro and in vivo. PA000214-PA1080: VEGF Polyclonal Antibody Rabbit Polyclonal Antibody. Specificity/Sensitivity: Human, mouse, rat. No cross reactivity with other proteins. Applications: Western blot: At 0.5-1 ug/ml with the appropriate system to detect VEGF in cells and tissues. Immunohistochemistry(P): At 1-2ug/ml to detect VEGF in formalin fixed and paraffin embedded tissues. Boiling the sections is required. Reactivity: Human, Mouse, Rat. Immunogen: A synthetic peptide corresponding to a sequence near the N-teminal end of VEGF of human origin, identical to the related rat sequences. Purification: Immunogen affinity purified. Form of Antibody: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3. Isotype: Rabbit IgG. Storage/Stability: Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original vial after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing. Other VEGF Antibodies: VEGF Polyclonal Antibody VEGF Monoclonal Antibody VEGF ELISA Kits: Rat VEGF ELISA Kit Mouse VEGF ELISA Kit Human VEGF ELISA Kit