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Product Name :
Tusamitamab Biosimilar, CEACAM5 Monoclonal Antibody

EN
Carcinoembryonic Antigen-related Cell Adhesion Molecule 5

Source:
The anti-human CEACAM5 monoclonal antibody tusamitamab biosimilar was produced in mammalian cells.

Molecular Weight:

Activity :

Purity:
>95% by SDS-PAGE under reducing conditions and HPLC.

Endotoxin :
< 1 EU per 1 mg of the protein by the LAL method.

Formulation:

Reconstitution :

Shipping:
The research grade tusamitamab biosimilar is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage:
/strong>Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

Form of Antibody :
0.2 uM filtered solution, pH 7.4, no stabilizers or preservatives.

Clone:

Isotype:
Human IgG1 kappa.

Background:
What is tusamitamab biosimilar research grade? Tusamitamab is a humanized IgG1-kappa monoclonal antibody targeting carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5) which is overexpressed in tumors including non-small cell lung cancer (NSCLC) and pancreatic ductal adenocarcinoma (PDAC), and is an attractive target for therapies based on CAR-T cell or/and ADCs. Tusamitamab ravtansine (SAR408701) is an antibody-drug conjugate (ADC) combining a humanized monoclonal antibody and a potent cytotoxic maytansinoid derivative (DM4) inhibiting microtubule assembly. Tusamitamab biosimilar uses the same protein sequences as the therapeutic antibody tusamitamab.Syd Labs provides the following research grade antibody biosimilars used in ADCs:Tusamitamab biosimilar, research grade, anti-human CEACAM5 monoclonal antibodyRovalpituzumab biosimilar, research grade, anti-human DLL3 monoclonal antibodyTrastuzumab biosimilar, research grade, anti-human HER2 monoclonal antibodyCofetuzumab biosimilar, research grade, anti-human PTK7 monoclonal antibodyIfinatamab biosimilar, research grade, anti-human B7-H3 (CD276) monoclonal antibodySacituzumab biosimilar, research grade, anti-human Trop-2 monoclonal antibodyGemtuzumab biosimilar, research grade, anti-human CD33 monoclonal antibodyPolatuzumab biosimilar, research grade, anti-human CD79B monoclonal antibodyCetuximab biosimilar, research grade, anti-human EGFR monoclonal antibody

Additional Information:
C109P: Tusamitamab Biosimilar, CEACAM5 Monoclonal AntibodyRecombinant Humanized IgG1 Monoclonal Antibody.|Isotype: Human IgG1 kap|The anti-human CEACAM5 monoclonal antibody tusamitamab biosimilar was produced in mammal cells.|Specificity/Sensitivity: The in vivo grade tusamitamab biosimilar specifically binds to the CEACAM5 protein.|Applications: ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological |0.2 uM filtered solution, pH 7.4, no stabilizers or preservatives.|Endotoxin: |Purity: >95% by SDS-|The research grade tusamitamab biosimilar is shipped with ice |Use a manual defrost freezer and avoid repeated freeze-thaw cycles.12 months from date of receipt, -20 to -70°C as supplied.1 month from date of receipt, 2 to 8°C as supplied.|BackgroundWhat is tusamitamab biosimilar research grade? Tusamitamab is a humanized IgG1-kappa monoclonal antibody targeting carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5) which is overexpressed in tumors including non-small cell lung cancer (NSCLC) and pancreatic ductal adenocarcinoma (PDAC), and is an attractive target for therapies based on CAR-T cell or/and ADCs. Tusamitamab ravtansine (SAR408701) is an antibody-drug conjugate (ADC) combining a humanized monoclonal antibody and a potent cytotoxic maytansinoid derivative (DM4) inhibiting microtubule assembly. Tusamitamab biosimilar uses the same protein sequences as the therapeutic antibody tusamitamab.Syd Labs provides the following research grade antibody biosimilars used in ADCs:Tusamitamab biosimilar, research grade, anti-human CEACAM5 monoclonal antibodyRovalpituzumab biosimilar, research grade, anti-human DLL3 monoclonal antibodyTrastuzumab biosimilar, research grade, anti-human HER2 monoclonal antibodyCofetuzumab biosimilar, research grade, anti-human PTK7 monoclonal antibodyIfinatamab biosimilar, research grade, anti-human B7-H3 (CD276) monoclonal antibodySacituzumab biosimilar, research grade, anti-human Trop-2 monoclonal antibodyGemtuzumab biosimilar, research grade, anti-human CD33 monoclonal antibodyPolatuzumab biosimilar, research grade, anti-human CD79B monoclonal antibodyCetuximab biosimilar, research grade, anti-human EGFR monoclonal antibody

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: signsin1dayinc