TRPV6 Antibody

Additional Information:
|Background TRPV6 (Transient Receptor Potent Cation Channel Subfamily V Member 6), also known as ECAC2, CAT1 or CATL, a membrane calcium channel which is responsible for the first step in calcium absorption in the intestine. TRPV6 is a member of the Transient receptor potent (TRP) family of membrane proteins. Using FISH, Peng et al. (2000) mapped the TRPV6 gene to chromosome 7q33-q34. Peng et al. (2000) determined that TRPV6 med calcium uptake independent of sodium, chloride, and hydrogen; however, calcium influx was higher at alkaline rather than acidic pH. Functional analysis by Peng et al. (2001) indicated that TRPV5 med greater calcium uptake than TRPV6. They concluded that TRPV5 and TRPV6 are calcium-selective channels and share a common ancestral gene. | TRPV6 Polyclonal Antibody Rabbit Polyclonal Antibody. Applications: WB 0.1-0.5 ug/ml. Reactivity: Human, Rat. Immunogen: A synthetic peptide corresponding to a sequence at the N-terminal of human TRPV6, different from the related rat sequence by one amino acid, and from the mouse sequence by two amino acids. Purification: Immunogen affinity purified. Form of Antibody: Lyophilized. Each v contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3. Isotype: Rabbit IgG. Storage/Stability: At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.