Product Name :
TRPV3 Antibody
EN
Transient Receptor Potential Cation Channel Subfamily V Member 3, VRL3
Additional Information:
|Background TRPV3 (Transient Receptor Potent Cation Channel Subfamily V Member 3), also known as VRL3, is a human gene encoding the protein of the same name. The TRPV3 protein belongs to a family of nonselective cation channels that function in a variety of processes, including temperature sensation and vasoregulation. Peier et al. (2002) localized the TRPV3 gene to a BAC clone mapped to chromosome 17p13. They mapped the mouse gene to chromosome 11B4. Peier et al. (2002) stably expressed mouse Trpv3 in Chinese hamster ovary cells and assayed electrophysiologic activity by whole cell voltage-clamp techniques. They determined that Trpv3 is a cation-permeable channel activated by warm and hot temperatures. Xu et al. (2002) showed that increasing temperature from approximately 22 to 40 degrees Celsius in mammal cells transfected with human TRPV3 elevated intracellular calcium by activating a nonselective cationic conductance. | TRPV3 Polyclonal Antibody Rabbit Polyclonal Antibody. Applications: WB 0.1-0.5 ug/ml. Reactivity: Human. Immunogen: A synthetic peptide corresponding to a sequence at the C-terminal of human TRPV3, different from the related rat and mouse sequences by four amino acids. Purification: Immunogen affinity purified. Form of Antibody: Lyophilized. Each v contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3. Isotype: Rabbit IgG. Storage/Stability: At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
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