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Product Name :
CD14 Antibody

EN
Monocyte differentiation antigen CD14, Myeloid cell-specific leucine-rich glycoprotein

Additional Information:
|Introduction CD14 (also known lipopolysaccharide (LPS) receptor) is expressed strongly on monocytes and macrophage and weakly on the surface of neutrophils. CD14 is anchored to cells by linkage to glycosylphosphatidylinositol (GPI) and functions as a high affinity receptor for complexes of LPS and LPS binding protein (LBP). Soluble CD14, also binding to LPS, acts at physiological concentration as an LPS agonist and has, at higher concentrations, an LPS antagonizing effect in cell activation. CD14 has been shown to bind apoptotic cells. | CD14 Monoclonal Antibody Mouse Monoclonal Antibody. Applications: Blocking and staining antibody. For staining, use 10 ul/106 cells. Titer for blocking LPS binding should be determined by the investigator. Reactivity: Human. Immunogen: Purified human B Cells Ig SubclassMouse IgG1. Purification: Ion exchange column. Form of Antibody: 1ug/ml in PBS (after reconstitution). Clone: hCD4. Isotype: Mouse IgG1. Storage/Stability: Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original v after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing.

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: signsin1dayinc