Trastuzumab Biosimilar, HER2 Monoclonal Antibody

Additional Information:
| Trastuzumab Biosimilar, HER2/ErbB-2/c-neu Monoclonal Antibody Recombinant Humanized IgG1 Monoclonal Antibody. Isotype: Human IgG1 kap|The monoclonal antibody trastuzumab biosimilar was produced in the trastuzumab biosimilar CHO stable cell line, which is available for licensing to manufacture the trastuzumab biosimilar protein. Specificity/Sensitivity: The monoclonal antibody trastuzumab biosimilar specifically binds to the human HER2 / ErbB-2 / c-neu. Applications: ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological |0.2 uM filtered solution, pH 6.0, no stabilizers or preservatives. Endotoxin: Purity: >95% by SDS-|The monoclonal antibody trastuzumab biosimilar is shipped with ice |Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70°C as supplied. 1 month from date of receipt, 2 to 8°C as supplied. |Background Trastuzumab, a humanized monoclonal antibody, interferes with the HER2/neu receptor and is mainly used to treat certain breast cancers, espec HER2-positive metastatic breast cancer. Combined with chemotherapy, trastuzumab increases both survival and response rate. There are four closely related receptor tyrosine kinases in the ErbB family of receptors: EGFR (ErbB-1; HER1 in humans), HER2/c-neu (ErbB-2), Her 3 (ErbB-3) and Her 4 (ErbB-4). Bound by members of the epidermal growth factor family (EGF-family) of extracellular protein ligands, the HER receptors embedded in the cell membrane promote cell growth and division by turning genes on and off. The HER2 ||Bevacizumab Biosimilar, research grade (VEGF-A) Ranibizumab Biosimilar, research grade (VEGF-A, Fab produced in E. coli) Cetuximab Biosimilar, research grade (HER1, ErbB-1, EGFR) |Tusamitamab biosimilar, research grade, anti-human CEACAM5 monoclonal antibody Rovalpituzumab biosimilar, research grade, anti-human DLL3 monoclonal antibody Trastuzumab biosimilar, research grade, anti-human HER2 monoclonal antibody Cofetuzumab biosimilar, research grade, anti-human PTK7 monoclonal antibody Ifinatamab biosimilar, research grade, anti-human B7-H3 (CD276) monoclonal antibody Sacituzumab biosimilar, research grade, anti-human Trop-2 monoclonal antibody Gemtuzumab biosimilar, research grade, anti-human CD33 monoclonal antibody Polatuzumab biosimilar, research grade, anti-human CD79B monoclonal antibody Cetuximab biosimilar, research grade, anti-human EGFR monoclonal antibody