Product Name :
CD11b Antibody
EN
Integrin alpha-M, Cell surface glycoprotein MAC-1 subunit alpha, CR-3 alpha chain, Leukocyte adhesion receptor MO1
Additional Information:
|Introduction Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 (‘Mac-1’), or inactivated-C3b (iC3b) receptor 3 (‘CR3’). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated |Blocking and staining antibody. For staining, use 10 ul/106 cells. Titer for blocking LPS binding should be determined by the investigator. Reactivity: Human. Immunogen: Purified human PBL Monocytes. Purification: Ion exchange column. Form of Antibody: 1ug/ml in PBS (after reconstitution). Clone: hCD11b. Isotype: Mouse IgG1. Storage/Stability: Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original v after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing.
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