Product Name :
TIMP3 Antibody
EN
Tissue inhibitor of metalloproteinase 3 Antibody
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The tissue inhibitors of metalloproteinases (TIMPs) are natural inhibitors of the matrix metalloproteinases, a group of zinc-binding endopeptidases involved in the degradation of the extracellular matrix. The TIMP3 gene is expressed in many tissues, with highest expression in the placenta. TIMP3 encodes a potent angiogenesis inhibitor and is mutated in Sorsby fundus dystrophy, a macular degenerative disease with submacular choroidal neovascularization. TIMP3 gene is mapped to 22q12.1-q13.2. Mutations in TIMP3 cause the autosomal dominant disorder Sorsby’s fundus dystrophy (SFD). PA000217-PA1077: TIMP3 Polyclonal Antibody Rabbit Polyclonal Antibody. Specificity/Sensitivity: Human, mouse, rat. No cross reactivity with other proteins. Applications: WB: 1:500~1:1000; ELISA: 1:10000. Reactivity: Human, Mouse, Rat. Immunogen: A peptide mapping at the C-terminal end of TIMP-3 of human origin, different to the related rat sequence by single amino acid. Purification: Immunogen affinity purified. Form of Antibody: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3. Isotype: Rabbit IgG. Storage/Stability: Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original vial after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing. Other TIMP3 Antibodies: TIMP3 Polyclonal Antibody TIMP3 Polyclonal Antibody
Additional Information:
|Background The tissue inhibitors of metalloproteinases (TIMPs) are natural inhibitors of the matrix metalloproteinases, a group of zinc-binding endopeptidases involved in the degradation of the extracellular matrix. The TIMP3 gene is expressed in many tissues, with highest expression in the placenta. TIMP3 encodes a potent angiogenesis inhibitor and is mutated in Sorsby fundus dystrophy, a macular degenerative disease with submacular choroidal neovascularization. TIMP3 gene is mapped to 22q12.1-q13.2. Mutations in TIMP3 cause the autosomal dominant disorder Sorsby’s fundus dystrophy (SFD). | TIMP3 Polyclonal Antibody Rabbit Polyclonal Antibody. Specificity/Sensitivity: Human, mouse, rat. No cross reactivity with other proteins. Applications: WB: 1:500~1:1000; ELISA: 1:10000. Reactivity: Human, Mouse, Rat. Immunogen: A peptide mapping at the C-terminal end of TIMP-3 of human origin, different to the related rat sequence by single amino acid. Purification: Immunogen affinity purified. Form of Antibody: Each v contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3. Isotype: Rabbit IgG. Storage/Stability: Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original v after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing. |Other TIMP3 Antibodies: TIMP3 Polyclonal Antibody TIMP3 Polyclonal Antibody
Related websites: https://www.medchemexpress.com/antibodies.html
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