Product Name :
Bis-propargyl-PEG8
Description:
Bis-propargyl-PEG8 (compound 16e) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
CAS:
1092554-87-4
Molecular Weight:
446.53
Formula:
C22H38O9
Chemical Name:
4,7,10,13,16,19,22,25,28-nonaoxahentriaconta-1,30-diyne
Smiles :
C#CCOCCOCCOCCOCCOCCOCCOCCOCCOCC#C
InChiKey:
MBRUWMSMSQUEOD-UHFFFAOYSA-N
InChi :
InChI=1S/C22H38O9/c1-3-5-23-7-9-25-11-13-27-15-17-29-19-21-31-22-20-30-18-16-28-14-12-26-10-8-24-6-4-2/h1-2H,5-22H2
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Bis-propargyl-PEG8 (compound 16e) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.|Product information|CAS Number: 1092554-87-4|Molecular Weight: 446.53|Formula: C22H38O9|Chemical Name: 4,7,10,13,16,19,22,25,28-nonaoxahentriaconta-1,30-diyne|Smiles: C#CCOCCOCCOCCOCCOCCOCCOCCOCCOCC#C|InChiKey: MBRUWMSMSQUEOD-UHFFFAOYSA-N|InChi: InChI=1S/C22H38O9/c1-3-5-23-7-9-25-11-13-27-15-17-29-19-21-31-22-20-30-18-16-28-14-12-26-10-8-24-6-4-2/h1-2H,5-22H2|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{CNTF Protein, Mouse} site|{CNTF Protein, Mouse} Protocol|{CNTF Protein, Mouse} References|{CNTF Protein, Mouse} manufacturer|{CNTF Protein, Mouse} Epigenetic Reader Domain} |Shelf Life: ≥12 months if stored properly.{{Flecainide} MedChemExpress|{Flecainide} Sodium Channel|{Flecainide} Biological Activity|{Flecainide} In stock|{Flecainide} manufacturer|{Flecainide} Epigenetics} |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:35901518 |Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.|References:|Jervis PJ, et al. Towards multivalent CD1d ligands: synthesis and biological activity of homodimeric α-galactosyl ceramide analogues. Carbohydr Res. 2012 Jul 15;356:152-62.Products are for research use only. Not for human use.|
