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Product Name :
Spectrin (alpha and beta) Antibody

EN

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Spectrin, the predominant component of the membrane skeleton of the red cell, is essential in determining the properties of the membrane including its shape and deformability. It consists of 2 nonidentical subunits, alpha and beta. Spectrin is present in the red cell membrane in a tetrameric or possibly higher polymeric form through head-to-head self-association of heterodimers that are linked by actin polymers and protein 4.1 to form a 2-dimensional network. Non-erythroid spectrin gene is mapped to human chromosome 2.Spectrin mutations cause spinocerebellar ataxia type 5. PA000087-MA1090: Spectrin (α and β) Monoclonal Antibody Mouse Monoclonal Antibody. Specificity/Sensitivity: Human. No cross reactivity with other proteins. Applications: Western blot: At 2-4 ug/ml with the appropriate system to detect spectrin in cells and tissues. Reactivity: Human. Immunogen: Human erythrocyte spectrin. Purification: Purified by the goat anti-mouse IgG affinity chromatography. Form of Antibody: Lyophilized from 1.2% sodium acetate, with 2 mg BSA and 0.01 mg NaN3 as preservative. Clone: Spe 1/2. Isotype: Mouse IgG1. Storage/Stability: Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original vial after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing.

Additional Information:
|Background Spectrin, the predominant component of the membrane skeleton of the red cell, is essent in determining the properties of the membrane including its shape and deformability. It consists of 2 nonidentical subunits, alpha and beta. Spectrin is present in the red cell membrane in a tetrameric or possibly higher polymeric form through head-to-head self-assoc of heterodimers that are linked by actin polymers and protein 4.1 to form a 2-dimensional network. Non-erythroid spectrin gene is mapped to human chromosome 2.Spectrin mutations cause spinocerebellar atax type 5. | Spectrin (α and β) Monoclonal Antibody Mouse Monoclonal Antibody. Specificity/Sensitivity: Human. No cross reactivity with other proteins. Applications: Western blot: At 2-4 ug/ml with the appropr system to detect spectrin in cells and tissues. Reactivity: Human. Immunogen: Human erythrocyte spectrin. Purification: Purified by the goat anti-mouse IgG affinity chromatography. Form of Antibody: Lyophilized from 1.2% sodium acetate, with 2 mg BSA and 0.01 mg NaN3 as preservative. Clone: Spe 1/2. Isotype: Mouse IgG1. Storage/Stability: Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original v after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing.

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: signsin1dayinc