Product Name :
SOCS1 Antibody
EN
Suppressor of cytokine signaling 1 Antibody
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Suppressor of cytokine signaling 1 (SOCS1), also known as Jak-binding protein (JAB), is a negative regulator to a subset of protein-tyrosine kinases. This 211-amino acid protein has a molecular mass of about 23.5 kD. The TEC-binding region of SOCS1 resides in the N terminus. SOCS1 associates with Tec and suppresses its kinase activity.1 The SOCS1 gene is intronless and is mapped to on chromosome 16p13.13.2 SOCS1 regulates the JAK/STAT signal-transduction pathway.3 Moreover, it contributes to protection against hepatic injury and fibrosis, and may also protect against hepatocarcinogenesis.4. PA000230-PA1074: SOCS1 Polyclonal Antibody Rabbit Polyclonal Antibody. Specificity/Sensitivity: Human, mouse, rat. No cross reactivity with other proteins. Applications: Western blot: At 1-2ug/ml with the appropriate system to detect SOCS1 in cells and tissues. Immunohistochemistry(P): At 0.5-1 ug/ml to detect SOCS1 in formalin fixed and paraffin embedded tissues. Reactivity: Human, Mouse, Rat. Immunogen: A synthetic peptide corresponding to a sequence at the C-terminal of human SOCS1, identical to the related mouse and rat sequence. Purification: Immunogen affinity purified. Form of Antibody: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3. Isotype: Rabbit IgG. Storage/Stability: Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original vial after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing. Other SOCS1 Antibody: SOCS1 Polyclonal Antibody
Additional Information:
|Background Suppressor of cytokine signaling 1 (SOCS1), also known as Jak-binding protein (JAB), is a negative regulator to a subset of protein-tyrosine kinases. This 211-amino acid protein has a molecular mass of about 23.5 kD. The TEC-binding region of SOCS1 resides in the N terminus. SOCS1 assoc with Tec and suppresses its kinase activity.1 The SOCS1 gene is intronless and is mapped to on chromosome 16p13.13.2 SOCS1 regulates the JAK/STAT signal-transduction |Human, mouse, rat. No cross reactivity with other proteins. Applications: Western blot: At 1-2ug/ml with the appropr system to detect SOCS1 in cells and tissues. Immunohistochemistry(P): At 0.5-1 ug/ml to detect SOCS1 in formalin fixed and |Human, Mouse, Rat. Immunogen: A synthetic peptide corresponding to a sequence at the C-terminal of human SOCS1, identical to the related mouse and rat sequence. Purification: Immunogen affinity purified. Form of Antibody: Each v contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3. Isotype: Rabbit IgG. Storage/Stability: Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original v after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing. |Other SOCS1 Antibody: SOCS1 Polyclonal Antibody
Related websites: https://www.medchemexpress.com/antibodies.html
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