SMAD7 Antibody

Additional Information:
|Introduction SMAD7(Mother against decapentaplegic drosophila homolog of 7), also known as MADH7 or SMA- AND MAD-RELATED PROTEIN 7, is a protein that in humans is encoded by the SMAD7 gene. It belongs to the SMAD family of proteins, which belong to the TGF? superfamily of ligands. By somatic cell hybrid analysis, Topper et al. (1997) mapped the MADH7 gene to human chromosome 18. Topper et al. (1997) demonstrated that MADH7 and MADH6 could form complexes in endothel cells. MADH7 was induced in cultured vascular endothelium by fluid mechanical forces and was ca|WB 0.1-0.5 ug/ml IHC-P 0.5-1 ug/ml. Reactivity: Human, Rat, Mouse. Immunogen: A synthetic peptide corresponding to a sequence at the C-terminal of human SMAD7, identical to the related rat and mouse sequences. Purification: Immunogen affinity purified. Form of Antibody: Lyophilized. Isotype: Rabbit IgG. Storage/Stability: Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original v after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing.