Product Name :
SKP2 Antibody
EN
S-phase kinase-associated protein 2 Antibody
Source:
Molecular Weight:
Activity :
Purity:
Endotoxin :
Formulation:
Reconstitution :
Shipping:
Stability & Storage:
Form of Antibody :
Clone:
Isotype:
Background:
The F box protein Skp2 (S-phase kinase-associated protein 2) is oncogenic, and its frequent amplification and overexpression correlate with the grade of malignancy of certain tumors. Skp2 controls p300-p53 signaling pathways in cancer cells, making it a potential molecular target for cancer therapy. This gene positively regulates the G(1)-S transition by controlling the stability of several G(1) regulators, such as the cell cycle inhibitor p27. This study provides evidence of a role for an F-box protein in oncogenesis and establishes SKP2 as a protooncogene causally involved in the pathogenesis of lymphomas. PA000235-PA1102: SKP2 Polyclonal Antibody Rabbit Polyclonal Antibody. Specificity/Sensitivity: Human, mouse, rat. No cross reactivity with other proteins. Applications: Western blot: At 1 ug/ml with the appropriate system to detect SKP2 in cells and tissues. Immunohistochemistry(P): At 1-2ug/ml to detect SKP2 in formalin fixed and paraffin embedded tissues. Reactivity: Human, Mouse, Rat. Immunogen: A synthetic peptide corresponding to a sequence at the N-terminal of human SKP2, different from the related rat and mouse sequence by three amino acids. Purification: Immunogen affinity purified. Form of Antibody: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3. Isotype: Rabbit IgG. Storage/Stability: Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original vial after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing. SKP2 Enzyme: Recombinant Human SKP2
Additional Information:
|Background The F box protein Skp2 (S-phase kinase-assoc protein 2) is oncogenic, and its frequent amplification and overexpression correlate with the grade of malignancy of certain tumors. Skp2 controls p300-p53 signaling |Human, mouse, rat. No cross reactivity with other proteins. Applications: Western blot: At 1 ug/ml with the appropr system to detect SKP2 in cells and tissues. Immunohistochemistry(P): At 1-2ug/ml to detect SKP2 in formalin fixed and |Human, Mouse, Rat. Immunogen: A synthetic peptide corresponding to a sequence at the N-terminal of human SKP2, different from the related rat and mouse sequence by three amino acids. Purification: Immunogen affinity purified. Form of Antibody: Each v contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3. Isotype: Rabbit IgG. Storage/Stability: Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original v after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing. |SKP2 Enzyme: Recombinant Human SKP2
Related websites: https://www.medchemexpress.com/antibodies.html
Popular product recommendations:
ATF6 Antibody (YA831)
PI 3 Kinase p85 alpha Antibody
FMRP Antibody: FMRP Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 71 kDa, targeting to FMRP. It can be used for WB, IF-Cell, IF-Tissue, IHC-P assays with tag free, in the background of Human, Mouse, Rat.
