ROR1 Antibody

Additional Information:
|Introduction ROR1(receptor tyrosine kinase-like orphan receptor 1), also known as neurotrophic tyrosine kinase, receptor-related 1 (NTRKR1), Tyrosine-protein kinase transmembrane receptor ROR1, is a member of thereceptor tyrosine kinase-like orphan receptor (ROR) family. NTRKR1 encodes a predicted 937-amino acid protein. A 6-kb NTRKR1 mRNA is expressed strongly in human heart, lung, and kidney, but weakly in the CNS. However, a truncated 2.4-kb mRNA lacking extracellular and transmembrane domains was strongly expressed in fetal and adult CNS and in a variety of human cancers, including those originating from CNS or PNS neuroectoderm. The protein encoded by this gene is a receptor tyrosine kinase that modulates neurite growth in the central nervous system. It is a type I membrane protein and belongs to the ROR subfamily of cell surface receptors. | ROR1 Polyclonal Antibody Rabbit Polyclonal Antibody. Applications: WB 0.1-0.5 ug/ml; IHC-P 0.5-1 ug/ml. Reactivity: Human, Rat, Mouse. Immunogen: A synthetic peptide corresponding to a sequence at the C-terminal of human ROR1, different from the related rat and mouse sequences by one amino acid. Purification: Immunogen affinity purified. Form of Antibody: Lyophilized. Isotype: Rabbit IgG. Storage/Stability: Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original v after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing.