Product Name: Manoalide
Synonyms: (5R)-4-[(2R,6R)-3,6-dihydro-6-hydroxy-5-[(3E)-4-methyl-6-(2,6,6-trimethyl-1-cyclohexen-1-yl)-3-hexen-1-yl]-2H-pyran-2-yl]-5-hydroxy-2(5H)-furanoneMedchemexpress
Product Overview: A natural sesterterpenoid which irreversibly inhibits sPLA2 isoforms from human synovium, bee venom, and cobra venom (IC50 values are 3.9, 7.5, and 2 μM, respectively); also potently blocks calcium channels (IC50 = 1 μM) and inhibits PLC (IC50 = 1.5
Shipping: wet ice
CAS NO: 781649-09-0 MK-0974
Stability: Store at -20 degrees; shelf life 180 days maximum after production
Molecular Formula: C25H36O5
SMILES: CC1=C(CC/C(C)=C/CCC2=CC[C@H](C([C@H](O)O3)=CC3=O)O[C@H]2O)C(C)(C)CCC1Dynamin inhibitors
Molecular Weight: 416.6
Formulation: A yellow solid
Purity: ≥98%PubMed ID:http://www.bloodjournal.org/content/127/11/1516