Product Name: GSK-J5 (hydrochloride)
Synonyms: N-[2-(3-pyridinyl)-6-(1,2,4,5-tetrahydro-3H-3-benzazepin-3-yl)-4-pyrimidinyl]-β-alanine, ethyl ester, monohydrochorideMedchemexpress
Product Overview: A pyridine regio-isomer of the JMJD3 inhibitor GSK-J4; cell-permeable and hydrolyzed to a free base, which is a weak inhibitor of JMJD3 (IC50 > 100 μM), making it an ideal negative control moleculeThe histone H3 lysine 27 (H3K27) demethylase JMJD3 p
Shipping: wet ice
CAS NO: 195733-43-8 Atrasentan (hydrochloride)
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C24H27N5O2 • HCl
SMILES: O=C(OCC)CCNC1=CC(N2CCC(C=CC=C3)=C3CC2)=NC(C4=CC=CN=C4)=N1.ClAntibody-drug Conjugate_ADC Related inhibitors
Molecular Weight: 454
Formulation: A crystalline solid
Purity: ≥95%PubMed ID:http://aac.asm.org/content/54/1/298.abstract
