Product Name: CCT137690
Synonyms: 6-bromo-7-[4-[(5-methyl-3-isoxazolyl)methyl]-1-piperazinyl]-2-[4-(4-methyl-1-piperazinyl)phenyl]-3H-imidazo[4,5-b]pyridineWeb Site click
Product Overview: A potent inhibitor of Aurora kinases (IC50s = 15, 25 and 19 nM for Aurora A, B, and C, respectively); also inhibits FLT3 as well as the constitutively active FLT3-ITD form (IC50s = 1.2 and 4.9 nM, respectively); orally bioavailable, inhibiting the growth
Shipping: wet ice
CAS NO: 941678-49-5 Ruxolitinib
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C26H31BrN8O
SMILES: CN(CC1)CCN1C(C=C2)=CC=C2C3=NC4=NC=C(Br)C(N5CCN(CC6=NOC(C)=C6)CC5)=C4N3IFNAR inhibitors
Molecular Weight: 551.5
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://www.bloodjournal.org/content/127/8/1062
