Product Name: Binimetinib
Synonyms: 5-[(4-bromo-2-fluorophenyl)amino]-4-fluoro-N-(2-hydroxyethoxy)-1-methyl-1H-benzimidazole-6-carboxamide ARRY-438162 Medchemexpress
Product Overview: An orally bioavailable inhibitor of MEK1/2 (IC50 = 12 nM) that inhibits ERK phosphorylation in various cancer cell lines (IC50s ≥ 5 nM); efficacious in several xenograft tumor models in mice, including those bearing K-Ras or B-Raf mutations, as well as
Shipping: wet ice
CAS NO: 57165-41-0 Product: Indoramin D5
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C17H15BrF2N4O3
SMILES: BrC1=CC(F)=C(NC2=C(F)C(N=CN3C)=C3C=C2C(NOCCO)=O)C=C1Sigma Receptor inhibitors
Molecular Weight: 441.2
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://aac.asm.org/content/57/7/3037.abstract
